While inhaled nicotine is so addictive that half of adult smokers smoke themselves to death, is it rational to take substantial comfort in the fact that vaping e-cigarettes is almost certainly less destructive?

While reflecting on the fact that most smoking-induced diseases take decades to develop, ask yourself this. How long will it be before science is confident that it knows most of the long-term consequences upon the body's 37 trillion cells of inhaling thousands of flavored nicotine cocktails, vaporized by 200 to 1,000°F coils within hundreds of unique vaping devices?

To help demonstrate the breadth and complexity of e-cigarette risk analysis, here's a sampling of 2022 nicotine, c-cig, and vaped flavoring findings:

While true that nicotine is a highly addictive natural insecticide and that once hooked it's as permanent as alcoholism, during and after recovery it's impossible to fail so long as all nicotine remains on the outside.

Nicotine's 2-hour elimination half-life guarantees that with 72 hours of ending nicotine use, your body will become 100% nicotine-free and your brain will have no choice but to begin the process of restoring natural sensitivities, as you sense moving beyond peak withdrawal. The worst behind you, within 21 days you'll begin feeling normal again as your brain completes the process of down-regulating receptor counts to levels seen in non-smokers.

There was always only one rule. On comfortable probation for the balance of life, for us, one puff will always be too many, while thousands won't be enough. Yes, just one rule ... no nicotine today ... to Never Take Another Puff!